Transformation of triclosan by Trametes versicolor and Pycnoporus cinnabarinus.

نویسندگان

  • K Hundt
  • D Martin
  • E Hammer
  • U Jonas
  • M K Kindermann
  • F Schauer
چکیده

We investigated the ability of Trametes versicolor and Pycnoporous cinnabarinus to metabolize triclosan. T. versicolor produced three metabolites, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-xylopyranoside, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-glucopyranoside, and 2,4-dichlorophenol. P. cinnabarinus converted triclosan to 2,4, 4'-trichloro-2'-methoxydiphenyl ether and the glucoside conjugate known from T. versicolor. The conjugates showed a distinctly lower cytotoxic and microbicidal activity than triclosan did.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 66 9  شماره 

صفحات  -

تاریخ انتشار 2000